Fungal vaccines and immunotherapeutics.

TILT Biotherapeutics.

8th vaccine renaissance: A creative nexus for vaccine developers.

Vaccine and Immunotherapeutic Approaches for the Prevention of Cryptococcosis: Lessons Learned from Animal Models

Cryptococcus neoformans and C. gattii, the predominant etiological agents of cryptococcosis, can cause life-threatening infections of the central nervous system in immunocompromised and immunocompetent individuals. Cryptococcal meningoencephalitis is the most common disseminated fungal infection in AIDS patients, and C. neoformans remains the third most common invasive fungal infection among or...

A novel multivalent tuberculosis vaccine confers protection in a mouse model of tuberculosis.

Mycobacterium tuberculosis infects one third of the world's population. Due to variable efficacy of the Bacille Calmette Guerin (BCG) vaccine, development of novel TB vaccines remains a priority. Here, we demonstrate the protective efficacy of a novel multivalent DNA vaccine, which contains 15 synthetic antigens targeting the Mtb ESX secretion system.

Human Vaccines and Immunotherapeutics: News

Agenus brain cancer vaccine improves survival in phase 2 trial: Meningococcal meningitis cases fall 94% following vaccine introduction: Most vaccines are safe during breastfeeding: Promising phase 1 results for Genocea's herpes simplex virus vaccine: Delayed vaccinations clearly increase risk of whooping cough: Positive news from early-stage HIV vaccines: Sanofi's H7N9 vaccine trial with MF59 a...